サル後根神経節細胞から上肢運動軌道を読み解く

Coding of forelimb trajectory in voluntary movement by peripheral afferents of monkeys

  • 梅田　達也 (生理学研究所認知行動発達研究機構)
  • 渡辺　秀典 (生理学研究所認知行動発達研究機構)
  • 佐藤　雅昭 (国際電気通信基礎技術研究所)
  • 川人　光男 (国際電気通信基礎技術研究所)
  • 伊佐　正(生理学研究所認知行動発達研究機構)
  • 西村　幸男 (生理学研究所認知行動発達研究機構)
  • Tatsuya Umeda (Dept. Dev. Physiol., NIPS)
  • Hidenori Watanabe (Dept. Dev. Physiol., NIPS)
  • Masa-aki Sato (ATR)
  • Mitsuo Kawato (ATR)
  • Tadashi Isa (Dept. Dev. Physiol., NIPS)
  • Yukio Nishimura (Dept. Dev. Physiol., NIPS)

We investigated whether population of DRG neurons could encode forelimb joint kinematics of behaving monkeys. Two multi-electrode arrays were chronically implanted in the C7 and C8 DRGs of two monkeys. Neuronal responses to reaching and grasping movements and 3-D trajectories of hand/arm movements were simultaneously recorded. 14 and 20 neurons were recorded in monkey 1 and 2, respectively. Using a sparse linear regression, forelimb joint kinematics could be reconstructed from activity of a subset of DRG ensembles. The result indicated that ensemble of peripheral afferents precisely coded forelimb joint kinematics in the voluntary reaching and grasping behavior of monkeys.
Last-modified: 2012-12-18 (火) 15:56:32